Are all biologic grafts the same?

No. Some biologic grafts are associated with higher rates of failure.(15)

Studies have shown long-term strength as the Biodesign® Hernia Graft remodels.(14)

Not only is the graft strong at the time of implant, it is designed to exceed the strength of the normal abdominal wall during the time it is being integrated into the patient’s body. When tissue repair and remodeling have been completed, the resulting tissue is stronger than that which was implanted. This occurs because Biodesign is an inductive scaffold—meaning that it is rapidly invaded by patient cells that reinforce the abdominal wall through the secretion of their own collagen.(14)


The technology behind Biodesign Hernia Graft has been designed to maintain strength throughout the remodelling process, so there is no need for chemical crosslinking.(14) Cross-linked grafts have been associated with chronic inflammation and encapsulation.(18)

As a non-dermis graft, the Biodesign Hernia Graft contains no meaningful amounts of elastin.(15) Dermis-based biologic grafts contain high amounts of elastin. Studies attribute higher rates of failure to higher elastin levels.(16, 17)