How to Use
Prepare the wound bed using standard-of-care methods. Remove debris and necrotic tissue from the wound. Be sure the wound has stopped bleeding. Cleanse the wound.
Cut the dry OASIS to cover slightly larger than the outline of the wound area. If the wound is larger than a single sheet, use multiple sheets. Overlap adjoining sheets to cover the entire wound.
Place the edges of OASIS in contact with the surrounding healthy tissue. Smooth OASIS in place so that the sheet is in contact with the underlying wound bed.
Rehydrate OASIS with sterile saline or other sterile isotonic solution. Alternatively, rehydrate OASIS before placing on the wound. Place it in a bowl of sterile saline or other isotonic solution for one minute before use.
Apply an appropriate porous, nonadherent dressing over OASIS. This nonadherent dressing will help secure OASIS to the wound bed, prevent the secondary dressing from adhering to OASIS, and lead to secondary dressing changes without disturbing OASIS.
Apply appropriate secondary dressings over the nonadherent dressing to maintain a moist wound environment. If the wound has heavy exudate, use an absorbent dressing. If the wound is dry, use a moisture-retentive dressing. Apply a cover dressing as needed to secure all layers. Change these dressings as needed. Do not dislodge OASIS from the wound bed.
As healing occurs, OASIS may darken in colour and form a caramel-coloured gel. This gel is normal. Do not remove it.
Reapply OASIS as needed. Typically, reapplication is needed every three to seven days. When preparing the wound for reapplication, do not forcibly remove any caramel-coloured gel from the wound. Gently cleanse the wound surface with sterile saline. Leave the caramel-coloured gel intact. Return to step 2 and repeat as needed